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By building on the capabilities of our staff and creating a culture that questions and challenges the way we do things, we strive to continuously evolve. Our working culture is open, creative, friendly and collaborative and we welcome applications from dynamic and experienced team members to help us achieve our ambitions and goals.
No recruitment agencies please as we will be unable to respond to you.
4basebio is an innovative gene synthesis company with the ambition to provide high quality, synthetic DNA for use in gene therapy, vaccines and gene editing platforms including RNA therapeutics. We are expanding our R&D teams at our site just North of Cambridge, UK to facilitate the scaling of our proprietary DNA manufacturing process including mRNA synthesis and development of nanoparticle vectors for nucleic acid delivery. We are looking for dynamic and experienced team members to help us achieve our ambitions and goals.
As the Quality Assurance Coordinator, this central administrative and specialist role within the Quality Assurance (QA) Team, will help to maintain an effective Quality Management System (QMS), and to achieve and maintain compliance with current Good Manufacturing Practices (cGMP).
Responsibilities:
- Support completion and record-keeping for key Quality elements such as document management, change control, Corrective and Preventative Actions (CAPAs), training and training record management
- Support material receipt checks and the pest control programme where necessary
- Support audits by customers and regulatory bodies as needed
- Support internal audits (self-inspections)
- Monitoring of Key Performance Indicators and metrics, as required
- Maintain QMS documentation through document control (issuance and reconciliation).
- Adhere to Good Documentation Practices, keep accurate records, follow instructions and comply with company policies in accordance with cGMP regulations
- Advocate the importance of Quality and compliance, and foster healthy collaborations with the Production, Warehouse, Facilities and Quality Control Teams
- Undertake any other appropriate tasks that reasonably fall within the role holder’s skills and experience, as requested
Person Specification:
- Educated to degree level and/or relevant experience
- Experience working in Quality Assurance is essential (Ideally pharmaceutical Quality Assurance)
- Demonstrable understanding of relevant Quality Management Systems
- Scrupulous attention to detail
- Comfortable working autonomously or collaboratively, and happy to undertake administrative tasks
- Methodical, organised and able to prioritise work effectively
- Extensive experience working with Microsoft Office applications, particularly Word and Excel
- Must hold the right to work in the UK
What we can offer:
Competitive salary + comprehensive benefits package
If you are interested in joining the 4basebio team, please forward your CV to HR@4basebio.com
Due to the high number of applicants, if you do not hear back from us within six weeks, we thank you for your interest, but please assume you have not been selected for interview on this occasion.
4basebio is an innovative gene synthesis company with the ambition to provide high quality, synthetic DNA for use in gene therapy, vaccines and gene editing platforms including RNA therapeutics. We are expanding our R&D teams at our site just North of Cambridge, UK to facilitate the scaling of our proprietary DNA manufacturing process including mRNA synthesis and development of nanoparticle vectors for nucleic acid delivery. We are looking for dynamic and experienced team members to help us achieve our ambitions and goals.
The primary focus of this role will be to contribute to new client or collaborator on nucleic acid synthesis projects and related R&D.
Responsibilities:
- Work as part of the RNA team, to be able of generating consistent and valuable data for collaborative and client based projects
- Perform screening and optimisation experiments using 4basebio DNA for in vitro RNA synthesis including RNA purification and analytics
- Evaluation of RNA mediated immune sensing using cellular reporter assays and cytokine profiling
- Execute and deliver projects to a high standard and in accordance with project plans
- Analyse and interpret experimental data; identify and solve experimental problems
- Work collaboratively and support the R&D functions of the company
- Record experimental methods and results to a high standard and in-line with company guidelines
- Attend and participate in relevant meetings, training, and development sessions
- Keep up to date with relevant scientific and technical developments
- Undertake any other appropriate roles and responsibilities that reasonably fall within the role holder’s skills and experience as requested
- Use and maintain company equipment in accordance with the company’s SOPs and health & safety guidelines
Person Specification:
- BSc/MSc in biological sciences, molecular biology, or a related life science field
- Hands-on experience working in molecular biology preferably RNA related projects in R&D labs
- Knowledge and practical experience in molecular biology and cellular techniques including cell handling, transfections, assays is desirable
- Experience in analytical techniques including agarose and polyacrylamide gel electrophoresis, nucleic acids quantification, capillary electrophoresis, ELISA, qPCR, flow cytometry
- Excellent record keeping skills
- Ability to test and troubleshoot new assays and techniques
- Excellent team working and communication skills
- Must hold the right to work in the UK
What we can offer:
Competitive salary + comprehensive benefits package
If you are interested in joining the 4basebio team, please forward your CV to HR@4basebio.com
Due to the high number of applicants, if you do not hear back from us within six weeks, we thank you for your interest, but please assume you have not been selected for interview on this occasion.
4basebio is an innovative gene synthesis company with the ambition to provide high quality, synthetic DNA for use in gene therapies and gene vaccines. We are expanding our teams at our premises just North of Cambridge, UK. We are looking for an experienced Safety Officer who is comfortable acting as the responsible person to ensure the company’s compliance with GMO/H&S legislation.
Responsibilities:
- Ensure the company’s compliance with GMO regulation in the workplace, i.e the Genetically Modified Organisms (Contained Use) Regulations 2014 (‘the GMO(CU) Regulations’), Health and Safety at Work Act 1974, the Management of Health and Safety at Work Regulations 1999, etc
- To be the main point of contact with the HSE and other H&S bodies/representatives, ensuring all required documentation is in place and filed in a timely manner
- Carry out risk assessment for GMO, H&S and Fire Safety, and action where additional measures may be required
- Adopt safe practices in activities involving biological material and assess the competence of persons to work safely
- Ensure all staff are adequately trained in H&S, especially new starters or staff who’s job role has significantly changed
- Investigate and record any accidents or incidents in liaison with the Lab Manager and/or the HR Manager taking appropriate action where needed
- Take on any other H&S responsibilities that reasonable fall within the job holders remit and capabilities
Person Specification:
- A good understanding of COSHH Regulations and the legal framework surrounding use of biological materials (e.g. GMO (Contained Use) regulations, SAPO, ACDP guidance etc.)
- Experience in managing the health, safety and welfare of staff over a multi-site environment
- Experience working in laboratory environments is essential
- Experience of working in cleanrooms and/or manufacturing environments is desirable
- Comfortable working autonomously or collaboratively
- Excellent communication skills
- Willing to travel between sites
- Must hold the right to work in the UK
What we can offer:
Competitive salary + comprehensive benefits package
If you are interested in joining the 4basebio team, please forward your CV to HR@4basebio.com
Due to the high number of applicants, if you do not hear back from us within six weeks, we thank you for your interest, but please assume you have not been selected for interview on this occasion.
Due to the high number of applicants, if you do not hear back from us within six weeks, we thank you for your interest, but please assume you have not been selected for interview on this occasion.
For more information and how our technologies can help you, please contact us
